"While we have successfully used Tucsen cameras with Windows systems for some time, Tucsen recently provided us with a dedicated driver for ARM-based embedded systems. This allows us to run these high-end scientific sensors natively on the Raspberry Pi within the openUC2 ecosystem."

– Dr. Benedict Diederich, OpenUC2 Co-Founder



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Group Research Aims

Dr. Benedict Diederich, along with Dr. René Lachmann, co-founded OpenUC2 to address a problem he repeatedly encountered in microscopy: every new optical experiment seemed to require building a custom system from scratch, making advanced imaging expensive, difficult to reproduce, and inaccessible to many researchers. Inspired by the modularity of electronics platforms such as Raspberry Pi and LEGO-style building systems, his goal is to democratize optics and microscopy by creating an open, low-cost, modular ecosystem that allows anyone to rapidly prototype, share, and reproduce optical instruments. The central challenge for the lab is reducing the complexity and cost barriers that surround modern microscopy, while the ultimate aim is to make advanced optical tools accessible, reproducible, and adaptable for researchers, educators, makers, and students worldwide.

Equipment & Experiment

OpenUC2's hardware ecosystem is built around a family of modular, open-source optical platforms designed to make advanced microscopy and imaging more accessible. You can even fully customise the optics online using YouSeeToo.

Tucsen's Libra series (16, 22, and 25) now have ARM drivers, enabling integration with embedded systems like the Raspberry Pi, enabling operation in the native openUC2 software: ImSwitch.

FRAME – a robust, modular mechanical architecture that allows researchers to rapidly assemble and modify microscopes, light-sheet systems, optical benches, and automation setups without the cost and complexity of traditional custom instrumentation. A micron-precise XYZ stage handles diverse samples up to multiwell scales, accommodates multiple objectives, and relies on built-in electronics (CANOpen) for synchronized motion, laser control, and camera triggering.

Integrating Tucsen’s scientific sensors introduces a new level of performance to openUC2, offering critical physical advantages:

  • Higher Quantum Efficiency: Maximizes light collection from weak signals, which is ideal for low-light fluorescence applications.
  • Larger Pixels & Higher Pixel Count: Provides a substantially larger Field of View (FOV) while maintaining detail and resolution.
  • Accelerated Scanning Routines: A larger FOV means fewer individual images (i.e., tiles) are needed to stitch a full sample, drastically speeding up histological scanning workflows.

Experience with Tucsen

"The power of this combination is demonstrated in the field: the system has successfully captured imaging data for DNA combing (the linearization and analysis of single DNA molecules). This application previously required expensive, proprietary instruments dedicated to a single task. openUC2 and Tucsen have made this capability accessible."

– Dr. Benedict Diederich, OpenUC2 Co-Founder

Libra 16 camera

Libra 16

The Libra 16 features a Sony sensor with a 16 mm field of view, allowing for high content imaging with classic sCMOS sensitivity.

  • 92% Peak QE @ 530 nm
  • 63 fps in 14-bit, 19 fps in 16-bit
  • 1.0 e- Read Noise
  • 2.3 Million Pixels
  • 7.52 Micron Pixels
  • USB3.0 Interface